This song was written by Bill Giant, Bernie Baum and Florence Kaye. Elvis recorded it on May 26, 1963 at RCA Studio B in Nashville.
Scotty Moore, Harold Bradley and Grady Martin all played guitar on the session, with Martin providing the "blistering guitar work", as Elvis researcher Ernst Jorgensen has referred to it. Other musicians included: Bob Moore (bass), D.J. Fontana (drums), Buddy Harman (drums), Floyd Cramer (piano) and Boots Randolph (sax and shakers). The Jordanaires and Millie Kirkham provided the backing vocals. On this session Hoyt Hawkins of The Jordanaires was replaced by Joe Babcock.
Take 6 was shipped out with "Please Don't Drag That String Around" as the B-side on June 18, 1963. "Devil in Disguise" peaked at #3 in its 11 weeks on Billboard's pop singles chart and peaked at #9 in its 8 weeks on the R&B chart. On the British pop singles chart it peaked at #1 for one week of its 12-week run.